Kind of hard to tell without more details. Which fuse is it? Typically this sort of problem happens for one of two reasons. Either there is too much load on the fuse i.e. you have a 30A appliance plugged into a 25A fuse, or could be something like a faulty appliance (refrigerator, water heater) that is drawing too much current. Or else there is a short to ground somewhere in that circuit.
2011 Chevy Silverado Crew Cab 4X4
2009 210 WBS